Shiraz E-Medical Journal

Published by: Kowsar

The Efficacy of Intrathecal Bupivacaine in Combination with General Anesthesia Versus General Anesthesia Alone on Time to Extubation in Patients With Coronary Artery Bypass Graft (CABG) Surgery

Zahra Pourmehdi 1 , Seyed Kamaleddin Tabatabaei 2 , Seyed Ahmadreza Salimbahrami 3 , * and Shiva Borzouei 4
Authors Information
1 Razi Hospital, Ahwaz University of Medica Sciences, Ahwaz, IR Iran
2 Emam Khomeini Hospital, Ahwaz University of Medical Sciences, Ahwaz, IR Iran
3 Besat Hospital, Hamadan University of Medical Sciences, Hamadan, IR Iran
4 Shahid Beheshti Hospital, Hamadan University of Medical Sciences, Hamadan, IR Iran
Article information
  • Shiraz E-Medical Journal: March 01, 2013, 14 (1); 13-20
  • Published Online: March 25, 2013
  • Article Type: Research Article
  • Received: May 7, 2012
  • Accepted: December 24, 2012

To Cite: Pourmehdi Z, Kamaleddin Tabatabaei S, Ahmadreza Salimbahrami S, Borzouei S. The Efficacy of Intrathecal Bupivacaine in Combination with General Anesthesia Versus General Anesthesia Alone on Time to Extubation in Patients With Coronary Artery Bypass Graft (CABG) Surgery, Shiraz E-Med J. 2013 ; 14(1):13-20.

Copyright © 2013, Shiraz University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Materials and Methods
4. Results
5. Discussion
  • 1. Priestley Mark C, Cope Louise, Halliwell Richard, Gibson Peter, Chard Richard B, Skinner Michael, et al. Thoracic epidural anesthesia for cardiac surgery: the effects on tracheal intubation time and length of hospital stay. Anesthesia & Analgesia. 2002; 94(2): 275-282
  • 2. MacAdams Charles, Fan Lawrence, Seal Douglas, Maier Karen, Kowalewski Richard, Tang Tim, et al. Combined general-spinal vs. general anesthesia for CABG. Canadian Journal of Anesthesia. 2003; 50(90001): 73
  • 3. Straka Zbynek, Brucek Petr, Vanek Tomas, Votava Jan, Widimsky Petr. Routine immediate extubation for off-pump coronary artery bypass grafting without thoracic epidural analgesia. The Annals of thoracic surgery. 2002; 74(5): 1544-1547
  • 4. Royse Colin, Royse Alistair, Soeding Paul, Blake Duncan, Pang Jenny. Prospective randomized trial of high thoracic epidural analgesia for coronary artery bypass surgery. The Annals of thoracic surgery. 2003; 75(1): 93-100
  • 5. Warltier David C, Myles Paul S, Daly David J, Djaiani George, Lee Anna, Cheng Davy CH. A systematic review of the safety and effectiveness of fast-track cardiac anesthesia. Anesthesiology. 2003; 99(4): 982-987
  • 6. Djaiani G. Thoracic epidural anesthesia as an adjunct to general anesthesia for cardiac surgery: Effects on ventilationperfusion relationships. Cardiothorac Vasc Anesth . 2000; 14(3): 359-60
  • 7. Scott Nicholas B, Turfrey Deborah J, Ray Dominic AA, Nzewi Onyukwelu, Sutcliffe Nicholas P, Lal Adarsh B, et al. A prospective randomized study of the potential benefits of thoracic epidural anesthesia and analgesia in patients undergoing coronary artery bypass grafting. Anesthesia & Analgesia. 2001; 93(3): 528-535
  • 8. Chaney Mark A. Intrathecal and epidural anesthesia and analgesia for cardiac surgery. Anesthesia & Analgesia. 2006; 102(1): 45-64
  • 9. Canver Charles C, Chanda Jyotirmay. Intraoperative and postoperative risk factors for respiratory failure after coronary bypass. The Annals of thoracic surgery. 2003; 75(3): 853-857
  • 10. Hein Ortrud Vargas, Birnbaum Jürgen, Wernecke Klaus D, Konertz Wolfgang, Jain Uday, Spies Claudia. Three-year survival after four major post-cardiac operative complications*. Critical care medicine. 2006; 34(11): 2729-2737
  • 11. Welsby Ian J, Bennett-Guerrero Elliott, Atwell Darryl, White William D, Newman Mark F, Smith Peter K, et al. The association of complication type with mortality and prolonged stay after cardiac surgery with cardiopulmonary bypass. Anesthesia & Analgesia. 2002; 94(5): 1072-1078
  • 12. Pulmonary complications after cardiac surgery. Seminars in cardiothoracic and vascular anesthesia. : 185-211
  • 13. Kowalewski Richard J, MacAdams Charles L, Eagle Chris J, Archer David P, Bharadwaj Baikunth. Anaesthesia for coronary artery bypass surgery supplemented with subarachnoid bupivacaine and morphine: a report of 18 cases. Canadian journal of anaesthesia. 1994; 41(12): 1189-1195
  • 14. Liu Spencer S, Block Brian M, Wu Christopher L. Effects of perioperative central neuraxial analgesia on outcome after coronary artery bypass surgery: a meta-analysis. Anesthesiology. 2004; 101(1): 153
  • 15. Barrington Michael J, Kluger Roman, Watson Robert, Scott David A, Harris Karen J. Epidural anesthesia for coronary artery bypass surgery compared with general anesthesia alone does not reduce biochemical markers of myocardial damage. Anesthesia & Analgesia. 2005; 100(4): 921-928
  • 16. Blomberg Sture G. Long‐Term Home Self‐Treatment with High Thoracic Epidural Anesthesia in Patients with Severe Coronary Artery Disease. Anesthesia & Analgesia. 1994; 79(3): 413-421
  • 17. Liu Spencer, Carpenter Randall L, Neal Joseph M. Epidural anesthesia and analgesia: their role in postoperative outcome. Anesthesiology. 1995; 82(6): 1474
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