Shiraz E-Medical Journal

Published by: Kowsar

Colorectal Carcinomas, a Consideration on MUTYH-Associated Polyposis

Tayebeh Hamzehloei 1 , * and Mahdieh Davoodnejad Dehsorkhi 1
Authors Information
1 Genetics Department, Medical School, Mashhad University of Medical Science, Mashhad, IR Iran
Article information
  • Shiraz E-Medical Journal: July 01, 2014, 15 (3); e21868
  • Published Online: July 20, 2014
  • Article Type: Review Article
  • Received: August 10, 2013
  • Revised: September 10, 2013
  • Accepted: January 20, 2014
  • DOI: 10.17795/semj21868

To Cite: Hamzehloei T, Davoodnejad Dehsorkhi M. Colorectal Carcinomas, a Consideration on MUTYH-Associated Polyposis, Shiraz E-Med J. 2014 ; 15(3):e21868. doi: 10.17795/semj21868.

Copyright © 2014, Shiraz University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Introduction
2. MutYH Gene and Protein
3. Identification and Characterization of MAP (MYH-Associated Polyposis)
4. Mutation spectrum
5. MutYH Mutation and CRC Risk
6. Molecular PROFILE of MAP Tumors
7. Genotype - Phenotype Correlation
8. MYH and Sporadic Cancers
9. Extracolonic Manifestations in MAP
10. Discussion
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