Shiraz E-Medical Journal

Published by: Kowsar

Comparison of Dysphonia Severity Index and its Parameters Among Individuals with Multiple Sclerosis and Healthy Subjects

Mahnoosh Fazeli 1 , Negin Moradi 1 , * , Majid Soltani 1 , Ehsan Naderifar 1 , Nastaran Majdinasab 2 and Seyed Mahmood Latifi 3
Authors Information
1 Musculoskeletal Rehabilitation Research Center, Department of Speech Therapy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
2 Musculoskeletal Rehabilitation Research Center, Department of Neurology, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
3 Health Research Institute, Diabetes Research Center, Department of Epidemiology and Statistics, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Article information
  • Shiraz E-Medical Journal: July 2018, 19 (7); e64857
  • Published Online: June 12, 2018
  • Article Type: Research Article
  • Received: December 7, 2017
  • Revised: January 24, 2018
  • Accepted: January 28, 2018
  • DOI: 10.5812/semj.64857

To Cite: Fazeli M, Moradi N, Soltani M, Naderifar E, Majdinasab N, et al. Comparison of Dysphonia Severity Index and its Parameters Among Individuals with Multiple Sclerosis and Healthy Subjects, Shiraz E-Med J. 2018 ; 19(7):e64857. doi: 10.5812/semj.64857.

Copyright © 2018, Shiraz E-Medical Journal. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited
1. Background
2. Methods
3. Results
4. Discussion
  • 1. Hartelius L, Nord L, Buder EH. Acoustic analysis of dysarthria associated with multiple sclerosis. Clin Linguist Phon. 2009;9(2):95-120. doi: 10.3109/02699209508985327.
  • 2. Duffy J. Motor Speech Disorders: Substrates. Differential Diagnosis and Management. 2nd ed. New York: Mosby; 2005. 592 p.
  • 3. LaDuke KM. Speech characteristics in multiple sclerosis. University of Wyoming; 2001.
  • 4. Rong P, Yunusova Y, Wang J, Green JR. Predicting Early Bulbar Decline in Amyotrophic Lateral Sclerosis: A Speech Subsystem Approach. Behav Neurol. 2015;2015:183027. doi: 10.1155/2015/183027. [PubMed: 26136624]. [PubMed Central: PMC4468279].
  • 5. Sapir S, Ramig LO, Spielman JL, Fox C. Formant centralization ratio: a proposal for a new acoustic measure of dysarthric speech. J Speech Lang Hear Res. 2010;53(1):114-25. doi: 10.1044/1092-4388(2009/08-0184). [PubMed: 19948755]. [PubMed Central: PMC2821466].
  • 6. Darley FL, Brown JR, Goldstein NP. Dysarthria in multiple sclerosis. J Speech Hear Res. 1972;15(2):229-45. doi: 10.1044/jshr.1502.229. [PubMed: 5047862].
  • 7. Hartelius L, Theodoros D, Cahill L, Lillvik M. Comparability of perceptual analysis of speech characteristics in Australian and Swedish speakers with multiple sclerosis. Folia Phoniatr Logop. 2003;55(4):177-88. doi: 10.1159/000071017. [PubMed: 12802090].
  • 8. Skodda S, Gronheit W, Schlegel U. Impairment of vowel articulation as a possible marker of disease progression in Parkinson's disease. PLoS One. 2012;7(2). e32132. doi: 10.1371/journal.pone.0032132. [PubMed: 22389682]. [PubMed Central: PMC3289640].
  • 9. Ziethe A, Patel R, Kunduk M, Eysholdt U, Graf S. Clinical analysis methods of voice disorders. Curr Bioinform. 2011;6(3):270-85. doi: 10.2174/157489311796904682.
  • 10. Kent RD, Weismer G, Kent JF, Vorperian HK, Duffy JR. Acoustic studies of dysarthric speech: methods, progress, and potential. J Commun Disord. 1999;32(3):141-80. quiz 181-3, 187-9. doi: 10.1016/S0021-9924(99)00004-0. [PubMed: 10382143].
  • 11. Wuyts FL, De Bodt MS, Molenberghs G, Remacle M, Heylen L, Millet B, et al. The dysphonia severity index: an objective measure of vocal quality based on a multiparameter approach. J Speech Lang Hear Res. 2000;43(3):796-809. doi: 10.1044/jslhr.4303.796. [PubMed: 10877446].
  • 12. Hakkesteegt MM, Brocaar MP, Wieringa MH, Feenstra L. The relationship between perceptual evaluation and objective multiparametric evaluation of dysphonia severity. J Voice. 2008;22(2):138-45. doi: 10.1016/j.jvoice.2006.09.010. [PubMed: 17570633].
  • 13. Maryn Y, Morsomme D, De Bodt M. Measuring the Dysphonia Severity Index (DSI) in the Program Praat. J Voice. 2017;31(5):644 e29-40. doi: 10.1016/j.jvoice.2017.01.002. [PubMed: 28187924].
  • 14. Zhou Z, Ge P, Liu Q, Liu M, Zhang W. [Observation of the dysphonia severity index in evaluating curative effect of vocal cord polyp surgery]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015;50(8):673-6. Chinese. [PubMed: 26696208].
  • 15. Aghadoost O, Amiri-Shavaki Y, Moradi N, Jalai S. A Comparison of Dysphonia Severity Index in Female Teachers With and Without Voice Complaints in Elementary Schools of Tehran, Iran. Nursing and Midwifery Studies. 2013;1(3):133-8. doi: 10.5812/nms.9904.
  • 16. Hakkesteegt MM, Brocaar MP, Wieringa MH. The applicability of the dysphonia severity index and the voice handicap index in evaluating effects of voice therapy and phonosurgery. J Voice. 2010;24(2):199-205. doi: 10.1016/j.jvoice.2008.06.007. [PubMed: 19185461].
  • 17. Nemr K, Simoes-Zenari M, de Souza GS, Hachiya A, Tsuji DH. Correlation of the Dysphonia Severity Index (DSI), Consensus Auditory-Perceptual Evaluation of Voice (CAPE-V), and Gender in Brazilians With and Without Voice Disorders. J Voice. 2016;30(6):765 e7-765 e11. doi: 10.1016/j.jvoice.2015.10.013. [PubMed: 26627119].
  • 18. Hakkesteegt MM, Brocaar MP, Wieringa MH, Feenstra L. Influence of age and gender on the dysphonia severity index. A study of normative values. Folia Phoniatr Logop. 2006;58(4):264-73. doi: 10.1159/000093183. [PubMed: 16825779].
  • 19. Dogan M, Midi I, Yazici MA, Kocak I, Gunal D, Sehitoglu MA. Objective and subjective evaluation of voice quality in multiple sclerosis. J Voice. 2007;21(6):735-40. doi: 10.1016/j.jvoice.2006.05.006. [PubMed: 16815671].
  • 20. Yamout B, Fuleihan N, Hajj T, Sibai A, Sabra O, Rifai H, et al. Vocal symptoms and acoustic changes in relation to the expanded disability status scale, duration and stage of disease in patients with multiple sclerosis. Eur Arch Otorhinolaryngol. 2009;266(11):1759-65. doi: 10.1007/s00405-009-1003-y. [PubMed: 19513739].
  • 21. Khorramshahi H, Heidari S, Goharpey S. [Comparison of jitter, shimmer and S/Z ratio in multiple sclerosis patients]. Jundishapur Sci Med J. 2013;6(11). Persian.
  • 22. Gosselink R, Kovacs L, Ketelaer P, Carton H, Decramer M. Respiratory muscle weakness and respiratory muscle training in severely disabled multiple sclerosis patients. Arch Phys Med Rehabil. 2000;81(6):747-51. [PubMed: 10857518].
  • 23. Feijo AV, Parente MA, Behlau M, Haussen S, de Veccino MC, Martignago BC. Acoustic analysis of voice in multiple sclerosis patients. J Voice. 2004;18(3):341-7. doi: 10.1016/j.jvoice.2003.05.004. [PubMed: 15331106].
  • 24. Konstantopoulos K, Vikelis M, Seikel JA, Mitsikostas DD. The existence of phonatory instability in multiple sclerosis: an acoustic and electroglottographic study. Neurol Sci. 2010;31(3):259-68. doi: 10.1007/s10072-009-0170-3. [PubMed: 19876591].
  • 25. Hartelius L, Buder EH, Strand EA. Long-term phonatory instability in individuals with multiple sclerosis. J Speech Lang Hear Res. 1997;40(5):1056-72. doi: 10.1044/jslhr.4005.1056. [PubMed: 9328877].
  • 26. Gerald FJF, Murdoch BE, Chenery HJ. Multiple sclerosis: Associated speech and language disorders. Aust J Hum Commun Disord. 2014;15(2):15-35. doi: 10.3109/asl2.1987.15.issue-2.02.
  • 27. Van Lierde KM, De Ley S, Clement G, De Bodt M, Van Cauwenberge P. Outcome of laryngeal manual therapy in four Dutch adults with persistent moderate-to-severe vocal hyperfunction: a pilot study. J Voice. 2004;18(4):467-74. doi: 10.1016/j.jvoice.2004.02.003. [PubMed: 15567048].
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments