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Development of Henoch_Schoenlein Vasculitis Following Ranitidine Administration in a Geriatric Patient

AUTHORS

MM Sagheb * , +

AUTHORS INFORMATION

ARTICLE INFORMATION

Shiraz E-Medical Journal: 7 (4); 1-4
Article Type: Case Report
Received: April 18, 2006
Accepted: August 15, 2006

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Abstract

Henoch_Schoenlein Vasculitis following drug administration is not so common. Here, a case of Henoch_Schoenlein Vasculitis caused by Ranitidine and Naproxen is described which presented with fever, vomiting bloody diarrhea, palpable purpura and azotemia. Histology of the skin showed leukocytoclastic vasculitis of superficial vessels and direct immunofluorescence revealed immunoglobulin A (IgA) in superficial dermal vessels and so confirmed the diagnosis. The patient was traeted with Ranitidine discontinuation and Prednisone administration. A short review of literature is also made

Keywords

Henoch_Schoenlein Vasculitis, Ranitidine, Naproxen

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