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Laboratory Diagnosis of Myeloperoxidase Deficiency: A Case Report.

AUTHORS

Zahra Pourmehdi 1 , Seyedkamaleddin Tabatabaei 2 , Seyedahmadreza Salimbahrami 1 , * , Shiva Borzouei 3

AUTHORS INFORMATION

1 Professor, Hematology and Oncology Resarch Center, Tabriz University of Medical Sciences

2 Clinica Fellow, Hematology and Oncology Resarch Center, Tabriz University of Medical Sciences

3 Research Assistant, Hematology and Oncology Resarch Center, Tabriz University of Medical Sciences

ARTICLE INFORMATION

Shiraz E-Medical Journal: 13 (1); e93925
Published Online: January 01, 2012
Article Type: Case Report
Received: May 18, 2019
Accepted: December 10, 2011

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Abstract

Myeloperoxidase deficiency is a common disorder featuring deficiency, either in quantity or function of Myeloperoxidase. The patients are misdiagnosed because majority of individuals with Myeloperoxidase deficiency show no signs of immunodeficiency. Myeloperoxidase defi-ciency is noted even before the diagnosis is suspected because the machines that perform automated leukocyte differential counts rely upon neutrophil Myeloperoxidase activity to enumerate these cells. This report describes two cases of myeloperoxidase deficiency that were diagnosed after reassess of the hemograms.In one case ,we got to the diagnosis after the patient went under Bone marrow Aspiration for ruling out leukemia.

Keywords

Myeloperoxidase neutrophil

© 2012, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
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