Solid Pseudopapillary Tumor of Pancreas: Presentations and Management

AUTHORS

Arash Mohammadi Tofigh 1 , * , Sh Rahmani 1 , M Mozaffar 2 , SM Abdollahi 3 , B Nemati Honar 3

1 Assistant Professor, Department of Surgery, Shahid Beheshti Uni- versity of Medical Sciences, Tehran, Iran

2 AssociateProfessor, Department of Surgery, Shahid Beheshti Uni- versity of Medical Sciences, Tehran, Iran

3 Resident, Department of Surgery, Shahid Beheshti Uni- versity of Medical Sciences, Tehran, Iran

How to Cite: Mohammadi Tofigh A, Rahmani S, Mozaffar M, Abdollahi S, Nemati Honar B. Solid Pseudopapillary Tumor of Pancreas: Presentations and Management, Shiraz E-Med J. Online ahead of Print ; 9(3):149-157.

ARTICLE INFORMATION

Shiraz E-Medical Journal: 9 (3); 149-157
Published Online: July 1, 2008
Article Type: Research Article
Received: October 18, 2007
Accepted: June 15, 2008

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Abstract

Objectives: To report a case series of pancreatic pseudopapillary solid cystic tumor as a rare low grade malignant abdominal tumor, which is relatively frequent in young women, with a discussion about its presentations and management to carry out a review of literature.

Materials and Methods: We report a case series of 5 Solid pseudopapillary tumors of pancreas .Then all published series of this tumor since 1952 will be analyzed according to our series. The reviewed parameters included demographic data clinical manifestations, therapeutic modalities, and clinical outcomes.

Results: Eighty percent of patients were female with mean age of 22.4 years. Two were presented with acute abdominal signs following blunt trauma, 2 with mass sensation, and 2 were incidentally found. They were all diagnosed pre-operatively through computed tomographic (CT) scan and all tumors had benign characteristics. No abnormalities were found in the follow up period and control CT scans.

Conclusion: Solid pseudopapillary tumors of pancreas have benign behavior, and the treatment of choice consists of surgical resection. It may spread outside the pancreas, particularly in peritoneal cavity. Metastatic spread may be promoted by trauma, including tumor biopsies, which should never be performed. The outcome after surgical resection is excellent with 90% survival in the long term. Recurrence has been reported in approximately 10% of patients.

Keywords

solid pseudopapillary tumor of the pancreas.

© 2008, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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